Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

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Tytuł oryginału: A study of thyroglobulin concentration in the thyroid and serum of patients with different thyroid disorders.
Autorzy: Czarnywojtek Agata, Krysińska Iwona, Łącka Katarzyna, Stawny Bolesław, Rólski Michał, Jarząb Barbara, Włoch Jan, Gembicki Maciej
Źródło: Arch. Immunol. Ther. Exp. 2002: 50 (2) s.143-148, il., tab., bibliogr. 19 poz.
Sygnatura GBL: 304,223

Hasła klasyfikacyjne GBL:
  • pediatria
  • endokrynologia

    Typ dokumentu:
  • praca kliniczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • dzieci 13-18 r.ż.
  • dorośli 19-44 r.ż.
  • dorośli 45-64 r.ż.
  • dorośli = 65 r.ż.
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: Knowledge concerning the structure and quality of thyroglobulin (tg) has great significance for the better understanding of the pathogenesis of different thyroid diseases. The localization of the Tg gene and studies of its structure by molecular biological techniques make possible precise investigations of its expression. The aim of our study was to evaluate Tg content in the thyroids and Tg concentrations in the serum of 108 patients suffering from beenign or malignant thyroid disorders. The method of investigation was isolating total protein from thyroid tissues obtained during surgery and determining Tg content in the thyroid extracts and Tg concentrations in serum The Tg concentrations in serum and in thyroid protein extracts were evaluated by fluoroimmunometric assay. Statisctical analysis was carried out with the help of the computing programmes.

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    Tytuł oryginału: Exposure to airborne microorganisms in furniture factories.
    Autorzy: Krysińska-Traczyk Ewa, Skórska Czesława, Cholewa Grażyna, Sitkowska Jolanta, Milanowski Janusz, Dutkiewicz Jacek
    Źródło: Ann. Agric. Environ. Med. 2002: 9 (1) s.85-90, il., tab., bibliogr. 57 poz.
    Sygnatura GBL: 313,158

    Hasła klasyfikacyjne GBL:
  • medycyna pracy
  • ochrona środowiska
  • mikrobiologia
  • pulmonologia

    Typ dokumentu:
  • praca doświadczalna
  • tytuł obcojęzyczny

    Streszczenie angielskie: Microbiological air sampling was performed in 2 furniture factories located in eastern Poland. In one factory furniture were made from fibreboards and chipboards while in the other from beech wood. It was found that the concentration of total microorganisms (bacteria + fungi) in the air of the facility using beech wood for furniture production (mean 10.7 x 10**3 cfu/m3, range 3.3 - 27.5 x 10**3 cfu/m**3) was significantly higher (p 0.01) compared to microbial concentration in the facility using fibre- and chipboards (mean 3.6 x 10**3 cfu/m3, range 1.9 - 6.2 x 10**3 cfu/m**3). On average, the commonest microorganisms in the air of the furniture factories were corynebacteria (Corynebacterium spp., Arthrobacter spp., Brevibacterium spp.) which formed 18.1 - 50.0 p.c. of the total airborne microflora, and fungi (mostly Aspergillus spp., Penicillium spp. and yeasts) which formed 6.2 - 54.4 p.c. of the total count. The values of the respirable fraction of airborne microflora in the furniture factories varied within fairly wide limits and were between 15.0 - 62.4 p.c. Altogether, 28 species or genera of bacteria and 12 species or genera of fungi were identified in the air of examined factories, of which respectively 8 and 7 species or genera were reported as having allegenic and/or immunotoxic properties. In conclusion, the workers of furniture factories are exposed to relatively low concentrations of airborne microorganisms which do not exceed the suggested occupational exposure limits. Nevertheless, the presence of allergenic and/or immunotoxic microbial species in the air of factories poses a potential risk of respiratory disease, in particular in sensitive workers.

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    Tytuł oryginału: Response of furniture factory workers to work-related airborne allergens.
    Autorzy: Skórska Czesława, Krysińska-Traczyk Ewa, Milanowski Janusz, Cholewa Grażyna, Sitkowska Jolanta, Góra Anna, Dutkiewicz Jacek
    Źródło: Ann. Agric. Environ. Med. 2002: 9 (1) s.91-97, tab., bibliogr. 46 poz.
    Sygnatura GBL: 313,158

    Hasła klasyfikacyjne GBL:
  • medycyna pracy
  • immunologia
  • pulmonologia

    Typ dokumentu:
  • praca epidemiologiczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • dorośli 19-44 r.ż.
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: The aim of this work was to determine the reactivity of furniture factory workers to microbial allegens associated with wood dust. Allergological examinations by skin and precipitin tests were performed in 48 workers employed in a factory producing furniture from fibreboards and chipboards, and in 32 healthy urban dwellers not exposed to organic dusts (referents). The skin test was performed by the intradermal method with the saline extracts of the cultures of 3 microbial species (Rahnella sp., Arthrobacter globiformis, Aspergillus fumigatus) associated with wood dust. Skin reactions were recorded after 20 minutes, 8 hours and 24 hours and graded 1 - 4, depending on the diameter of the reaction. The agar-gel test for the presence of precipitins in serum was performed with the extracts of 15 microbial isolates. The furniture factory workers showed a high skin response to the extracts of environmental microbes. The frequency of early grade 2 reactions (diameter 10 mm) to the extract of Rahnella sp. was 64.6 p.c. among furniture workers, being significantly higher (p 0.001) compared to reference group (18.7 p.c.). High frequencies of grade 2 reactions in furniture workers were also found with the extracts of A. globiformis and A. fumigatus (52.1 p.c. and 62.5 p.c., respectively). The frequencies of grade 2 delayed (after 8 h) and late (after 24 h) reactions to Rahnell sp. in furniture workers were non-specifically high (97.9 p.c./93.7 p.c.) while the response rates to A. globiformis and A. fumigatus were much lower (10.4 p.c./25.0 p.c., and 4.2 p.c./37.5 p.c., respectively). In agar-gel test for detection of precipitins, in most cases very low percentages...

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    Tytuł oryginału: Work-related symptoms among furniture factory workers in Lublin region (eastern Poland).
    Autorzy: Milanowski Janusz, Góra Anna, Skórska Czesława, Krysińska-Traczyk Ewa, Mackiewicz Barbara, Sitkowska Jolanta, Cholewa Grażyna, Dutkiewicz Jacek
    Źródło: Ann. Agric. Environ. Med. 2002: 9 (1) s.99-103, tab., bibliogr. 24 poz.
    Sygnatura GBL: 313,158

    Hasła klasyfikacyjne GBL:
  • medycyna pracy
  • pulmonologia

    Typ dokumentu:
  • praca epidemiologiczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • dorośli 19-44 r.ż.
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: 48 woodworkers employed in the furniture factory were examined. The control group consisted of 41 office workers with no exposure to organic dust. The examination included: interview on work-related symptoms, physical examination, and lung function test performed before and after the working-day. 38 out of 48 (79.2 p.c.) woodworkers reported work-related symptoms. The most common complaint was dry cough reported by 25 workers (52.1 p.c.), followed by general malaise - reported by 17 (35.45 p.c.), cojunctivitis - by 16 (33.3 p.c.), rhinitis - by 16 (33.3 p.c.), and skin symptoms by 16 (33.3 p.c.). Other symptoms such as headache, shortness of breath and chest pain occurred less frequently. Subjects working in initial processing and board processing departments had a higher prevalence of cough compared to workers employed in the varnishing depertment (p 0.01). The prevalence of skin symptoms was significantly higher in board preocessing and varnishing departments compared to initial processing department (p 0.05). Occupational asthma and allegic alveolitis were recorded in 3 out of 48 (6.2 p.c.) and 2 out of 48 (4.2 p.c.) workers, respectively. Baseline FVC adn FEV1 values were lower in woodworkers compared to controls (p 0.01). The increased lung function parameters (FVC, FEV1) were observed in woodworkers who smoked compared to non-smokers. The difference was not statistically significant. There was a significant over-shift decrease of all measured spirometric values: FVC, FEV1, FEV1/VC, PEF among woodworkers (p 0.001). There was a significant pre-shift, post-shift decline...

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    Tytuł oryginału: Exposure to airborne microorganisms and endotoxin in a potato processing plant.
    Autorzy: Dutkiewicz Jacek, Krysińska-Traczyk Ewa, Skórska Czesława, Cholewa Grażyna, Sitkowska Jolanta
    Źródło: Ann. Agric. Environ. Med. 2002: 9 (2) s.225-235, il., tab., bibliogr. 72 poz.
    Sygnatura GBL: 313,158

    Hasła klasyfikacyjne GBL:
  • medycyna pracy
  • mikrobiologia

    Typ dokumentu:
  • praca doświadczalna
  • tytuł obcojęzyczny

    Streszczenie angielskie: Microbiological air sampling was performed in a big potato processing plant located in eastern Poland. Air samples for determination of concentrations of microorganism, dust and endotoxin were collected at 6 sites in the division producing potato flakes and meal from dried potato pulp and at 2 sites in the division producing potato syrup from imported starch. The concentrations of total airborne microorganisms were within a range of 28.3 - 93.1 x 10**3. Mesophilic bacteria were dominant at all sampling sites, forming 73.1 - 98.8 p.c. of the total count. Among them, distinctly prevailed corynebacteria (irregular Gram-positive rods) that accounted for 54.3 - 81.1 p.c. of the total airborne microflora. The most common were strains of Corynebacterium spp., followed by strains of Arthrobacter spp., Microbacterium spp., and Agromyces ramosus. The later species, so far not reported from the air of occupational environments, abundantly develops in the parenchyma of potato tubers. Its airborne concentration increased rapidly after peeling of potatoes, and attained maximal values at cutting and blanching (steaming and sulfuration) of potatoes, and at sacking of potato meal. The proportions of Gram-negative bacteria and endospore-forming bacilli were low, respectively 0.6 - 7.6 p.c. and 2.0 - 8.1 p.c. of total count. Fungi constituted 1.2 - 26.9 p.c. of total count. The dominant species was Asprgillus niger that formed 99.8 p.c. of total airborne fungi. The values of the respiraable fraction of airborne microflora varied between 25.3 - 73.2 p.c. The concentrations of airborne dust were 1.4 - 26.6 mg/m3...

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    Tytuł oryginału: Precipitin response of potato processing workers to work-related microbial allergens.
    Autorzy: Dutkiewicz Jacek, Skórska Czesława, Krysińska-Traczyk Ewa, Cholewa Grażyna, Sitkowska Jolanta, Milanowski Janusz, Góra Anna
    Źródło: Ann. Agric. Environ. Med. 2002: 9 (2) s.237-242, il., tab., bibliogr. 43 poz.
    Sygnatura GBL: 313,158

    Hasła klasyfikacyjne GBL:
  • medycyna pracy
  • immunologia
  • mikrobiologia

    Typ dokumentu:
  • praca epidemiologiczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie
  • dorośli 19-44 r.ż.
  • dorośli 45-64 r.ż.
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: Serum samples from 61 potato processing workers and 30 urban dwellers not exposed to organic dusts (as a reference group) were examined in agar-gel precipitation test performed by Ouchterlony double diffusion method with the antigens of 12 microorganisms associated with organic dusts. Each serum was tested twice: not concentrated, and three-fold concentrated, for the detection of low levels of precipitins. The antibody response of workers to the antigen of coryneform bacterium Agromyces ramosus was high, at both not concentrated and 3-fold concentrated sera (respectively 29.5 p.c. and 45.9 p.c.) - significantly greater than in reference group (p 0.001). Workers' response to the antigens of Gram-negative bacterium Alcaligenes faecalis and thermophilic actinomycete Thermoactinomyces vulgaris was lower (respoectively 13.1 p.c. and 13.1 p.c. at not concentrated sera, 24.6 p.c. and 29.5 p.c. at 3-fold concentrated sera) but in all cases significantly greater than in reference group (p 0.05 at not concentrated sera, p 0.01 and p 0.001 at 3-fold concentrated sera). The frequency of positive precipitin reactions of potato workers to antigen of Penicllium citrinum was high only at 3-fold concentrated sera (55.7 p.c.) - significantly higher compared to reference group (p 0.001). The antibody response of potato workers to other antigens was either unspecific or low, showing no significant difference compared to reference group. Twenty eight out of 61 examined potato processing workers (45.9 p.c.) reported the occurence of the work related pulmonary symptoms. The frequency of postivie....

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    Tytuł oryginału: The effects of exposure to organic dust on the respiratory system of potato processing workers.
    Autorzy: Milanowski Janusz, Góra Anna, Skórska Czesława, Mackiewicz Barbara, Krysińska-Traczyk Ewa, Cholewa Grażyna, Sitkowska Jolanta, Dutkiewicz Jacek
    Źródło: Ann. Agric. Environ. Med. 2002: 9 (2) s.243-247, tab., bibliogr. 34 poz.
    Sygnatura GBL: 313,158

    Hasła klasyfikacyjne GBL:
  • medycyna pracy
  • pulmonologia

    Typ dokumentu:
  • praca epidemiologiczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie

    Streszczenie angielskie: A cross-sectional study was carried out to evaluate lung function and the prevalence of work-related symptoms in workers of a potato processing plant located in Lublin region (easern Poland). The study group comprised 61 workers employed in 2 depertments. The examination included: physician-administrated questionnaire on occurence of work-related symptoms, occupational history and smoking habits. Spirometry was performed before (7.00 - 8.00) and after (f16.00 - 17.00) the morning shift. Altogether 41/61 (67.2 p.c.) subjects reported at least one symptom associated with their job. Pulmonary symptoms were recorded in 28/61 (45.9 p.c.) subjects. The most commonly recorded complaints were: cough (44.3 p.c.), hoarseness (19.7 p.c.), shorteness of breath (f18 p.c.), followed by headache and skin lesion (13.1 p.c. each), and eye and nose irritation (11.5 p.c.). The prevalence of work-related symptoms (except for eye and nose irritation) was higher in the group of subjects wroking longer than 4 years (the difference was statistically significant only for skin lesion). Among non-smoking workers a significantly higher prevalence of headache was seen compared to smokers (Fisher's test, p 0.05). Smokers complained more frequently of respiratory symptoms such as cough, shortness of breath, hoarseness and chest pain. The difference was significant only for cough (p 0.05) A statistically sifnificant over-shift decline in all measured spirmoetric values: FVC, FEV1 (p 0.001), FEV1/VC (p 0.05), PEF (p 0.01) was observed.

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    Tytuł oryginału: Principal component analsyis of patient variables as an objective method of classification of thyroid disorders.
    Tytuł polski: Analiza składników głównych jako obiektywny sposób klasyfikacji schorzeń tarczycy.
    Autorzy: Buciński Adam, Krysińska Iwona, Sowiński Jerzy, Bączek Tomasz, Kaliszan Roman
    Źródło: Endokrynol. Pol. 2002: 53 (2) s.123-136, il., tab., bibliogr. 10 poz., streszcz.
    Sygnatura GBL: 304,167

    Hasła klasyfikacyjne GBL:
  • endokrynologia

    Typ dokumentu:
  • praca kliniczna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • ludzie

    Streszczenie polskie: Analiza składników głównych (principal component analysis, PCA) wykorzystana została do obiektywnej klasyfikacji pacjentów ze schorzeniami tarczycy. Analiza PCA została przeprowadzona na dużym zbiorze parametrów klinicznych. Metoda pozwoliła na ocenę złożonych zależności pomiędzy zmiennymi charakteryzującymi pacjentów i choroby, w konsekwncji umożliwiając klasyfikację poszczególnych schorzeń tarczycy. Studia przeprowadzono na grupie 230 pacjentów cierpiących na sześć schorzeń tarczycy. Pacjentów charakteryzowało 6 zmiennych, włączając płeć, wiek i oznaczony we krwi poziom pięciu hormonów. Macierz 230 x 6 została poddana analizie składników głównych wykorzystując komercyjnie dostępny program statystyczny i komputer osobisty. Wyekstrahowane dwa składniki główne, PC1 i PC2, opisują 63,09 proc. całkowitej zmienności próby. Wyraźne zróżnicowanie położeń punktów w przestrzeni wyznaczonej przez dwa pierwsze składniki główne interpretowano w kategoriach podobieństw (różnic) między przypadkami.

    Streszczenie angielskie: An advanced multivariate data processing method, principal component analysis (PCA), was demonstrated to provide an objective classification of patients with tyroid disorders by making use of large collections of routine clinical parameters of patients. The method allows for detection of complex systematic relationships between diverse patient and disease variables and hence for the classification of individual thyroid disorders. Two hundred thirty patients with six kinds of thyroid disorders were subjected to the study for whose seven variables including sex, age and blood level of five hormones were determined. A matrix of 230 x 7 data points was analyzed by PCA employing commercially available statistical software and a personal computer. Two principal components, PC1 and PC2, were extracted which accounted cumulatively for 63.09 p.c of the variance in the data set. A clear-cut clustering of patients have been observed, which are interpreted in terms of similarity (dissimilarity) of the variables and of the patients.

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