Wynik wyszukiwania w bazie Polska Bibliografia Lekarska GBL

Zapytanie: KOSIK-BOGACKA
Liczba odnalezionych rekordów: 6



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Tytuł oryginału: Model study of toluene diisocyanate effect on transepithelial ion transport.
Autorzy: Kosik-Bogacka Danuta Izabela, Tyrakowski Tomasz
Źródło: Med. Sci. Monitor 2002: 8 (5) s.BR187-BR192, il., tab., bibliogr. 36 poz.
Sygnatura GBL: 313,278

Hasła klasyfikacyjne GBL:
  • toksykologia

    Typ dokumentu:
  • praca doświadczalna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • zwierzęta
  • Żaby
  • in vitro

    Streszczenie angielskie: Toluene disocyanate (TDI), a low molecular weight compound, is commonly known as a factor causing asthma in chemical industry workers. The present study investigated a possible effect of TDI on ion transport using electrophysiological methods aimed at assessment of ion currents occurring in epithelial tissues. The experiemnts were carried out on 119 fragments of isolated frog skin, sampled from 59 specimens of hybrid frog Rana esculenta L. The procedures employed involved transepithelial electrical potential (PD in mV) measuremetn with an Ussing apparatus, modified to enable mechanical stimulation of organs and defined pharmacological actions. Incubation was carried out using Ringer solution and Ringer solution with amiloride and baumetanide. Direct actions of toluene diisocyanate (TDI) were assessed at the time of administering this substance to the Ussing chamber with a peristaltic pump. Based on the model of frog skin tested with Ussing apparatus, administration of TDI to the fluid stimulating preparations incubated with Ringer solution (RH) and with amiloride (AMI) was demonstrated to cause a hyperpolarization invrease after mechanical stimulation. TDI action on isolated frog skin inflicated a change in response to mechanical stimulation, leading to a depolarization. The reaction magnitude of frog skin incubated with bumetanide (BUME) did not chane due to TDI. TDI influences precesses of sodium ion transport in the isolated frog skin model, depending on mechanical stimulation. This indicates that TDI effect on ion transport in epithelial cells depends on C fibres and tachaykinins released from their endings.


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    Tytuł oryginału: Detection of Borrelia burgdorferi sensu lato in mosquitoes (Culicidae) in recreational areas of the city of Szczecin.
    Autorzy: Kosik-Bogacka Danuta, Bukowska Katarzyna, Kuźna-Grygiel Wanda
    Źródło: Ann. Agric. Environ. Med. 2002: 9 (1) s.55-57, tab., bibliogr. 29 poz.
    Sygnatura GBL: 313,158

    Hasła klasyfikacyjne GBL:
  • immunologia
  • mikrobiologia

    Typ dokumentu:
  • praca doświadczalna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • zwierzęta

    Streszczenie angielskie: The mosquitoes were caught within the period of their highest activity, i.e. June-August 2001, in recreational areas of the city of Szczecin. Spirochetes, Borrelia burgdorferi sensu lato were detected in mosquitoes with the aid of the method of indirect immunofluorescence (IFA) using rabbit anti-Borrelia burgdorfere antibodies and goat anti-rabbit IgG marked with fluorescein isothiocyanate (FITC). A total of 639 mosquito females representing genera A‰des (99.1 p.c.) and Culex (0.9 p.c.) were collected. The mean value of the infection rate of mosquitoes from the area studied was 1.25 p.c. The highest infection rate was recorded in June (3.2 p.c.), while the lowest - in July (0.6 p.c.). All mosquitoes infected with Borrelia burgdorferi spirochetes belonged to the gnus A‰des. The results of the present study confirm a potential role of those arthropods in epidemiology of Lyme borreliosis.


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    Tytuł oryginału: Effect of ambroxol on ion transport - a model study.
    Autorzy: Kosik-Bogacka Danuta I., Tyrakowski Tomasz
    Źródło: Med. Sci. Monitor 2002: 8 (6) s.BR236-BR241, il., tab., bibliogr. 44 poz.
    Sygnatura GBL: 313,278

    Hasła klasyfikacyjne GBL:
  • farmacja

    Typ dokumentu:
  • praca doświadczalna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • zwierzęta
  • Żaby

    Streszczenie angielskie: Effect on ambroxol on reflexive physiological reactions of isolated frog skin was studied with elctrophysiological methods designed to assess on currents occurring in epithelial tissues or organs. The experiments permitted to analyze an effect of ambroxol on regulatory mechanisms, which in turn influence the constant electrical potential defined as PD and reversible changes of this potential during mechanical stimulation (marked as dPD). A contribution of sodium- and chlorid eions transport to the value of transepithelial electrical potential of frog skin (before adn after ambroxol administration) has been demonstrated using amiloride - a blocker of sodium ion transport and bumetanide - a blocker of chloride ion transport. The experimental material comprised 34 fragments of hybrid frog (Rana esculenta L.),, representing 14 spcimens. The experiments involved measuring the transepthelial electrical potential (PD in mV) on an isolated frog skin place in an Ussing apparatus. It has been demonstrated that ambroxol influences the processes of ion transport (dPD) which in turn depend on mechanical stimulation. The reaction of hyperpolarization decreased immediately after administration of ambroxol to the stimulating fluid, when transepithelial transport of sodium ion was maintained in the preparations studied. Consequently, no efect of ambroxol on the frog skin incubated wtih amiloride was recorded. It has been demonstrated, based on the experiments carried out in the present study , taht ambroxol can modify processes of ion transport related to activation of sensory receptors...


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    Tytuł oryginału: Effect of capsaicin on ion transport in the caecum of rabbits.
    Autorzy: Kosik-Bogacka Danuta, Banach Bolesław, Tyrakowski Tomasz
    Źródło: Pol. J. Pharmacol. 2002: 54 (5) s.475-482, il., bibliogr. 38 poz.
    Sygnatura GBL: 313,156

    Hasła klasyfikacyjne GBL:
  • farmacja
  • gastroenterologia

    Typ dokumentu:
  • praca doświadczalna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • zwierzęta
  • króliki
  • płeć męska
  • płeć żeńska

    Streszczenie angielskie: Effect of capsaicin, a stimulator of C-fibres, on ion transport in the caecum of rabbits was studied using electrophysiological methods, designed to evaluate ionic currents occurring in epithelial tissues. The experiments consisted inmeasuring transepthelial electrical potential difference (dPD) of an isolated fragment of ragbbit's caecum, placed ina Ussing apparatus. The ion transport was modified through incubation in Ringer solution, supplemented with amiloride, bumetanide, and capsaicin. Capsaicin was also administred with persistalting pump. The experiments demonstrated that the inhibition of sodium ions transport caused by incubation with amiloride and incubation with capsaicin slowed down mechanical reaction to electrical potential difference. On the other hand, immediately after the other hand, immediately after the administration, the capsaicin effect on C-fibres modified electrophysiological reaction of the caecum to mechanical stimulation. Physiological and pharmacological experiemnts reveal that a component dependent on activation of C-fobres contributes to the reaction of ion transport activation following mechanical stimulation.


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    Tytuł oryginału: Effect of capsaicin and dimethyl sulfoxide on ion transport in the selected experimental models.
    Autorzy: Kosik-Bogacka Danuta I., Banach Bolesław, Tyrakowski Tomasz, Wojciechowska Iwona
    Źródło: Pol. J. Pharmacol. 2002: 54 (3) s.267-274, il., tab., bibliogr. 46 poz.
    Sygnatura GBL: 313,156

    Hasła klasyfikacyjne GBL:
  • farmacja

    Typ dokumentu:
  • praca doświadczalna
  • tytuł obcojęzyczny

    Wskaźnik treści:
  • zwierzęta
  • króliki
  • Żaby
  • in vitro

    Streszczenie angielskie: The aim of the present work was to determine the changes in ion transport in the selected epithelium-lined organs under influence of mechanical stimuli, and also to assess similarities and differences in reactions to capsaicin and dimethyl sulfoxide (DMSO) between trachea and caecum of rabbit and the skin of frog in this experimental setup. The experiments were conducted on rabbit trachea and caecum, and the skin of frog, Rana esculenta L. The experiments consisted in measuring transepithelial electrical potential (PD in mV) with Ussing apparatus, modified to enable testing of the effects of mechanical stimulation of organs and defined pharmacological treatments. It was demonstrated that the addition of DMSO to the stimulating fluid decreased reversible hyperpolarization (dPD) after mechanical stimulation by at least 50 p.c. in all studied groups. On the other hand, action of capsaicin was dependent on the organ studied as well as on experimental conditions (e.g. type of incubation). Capsaicin decreased PD and reaction to mechanical stimulation in trachea incubated in Ringer solution supplemented with amiloride. On the other hand, it did not influence electrophysiological parameters of the trachea following its incubation with bumetanide. Capsaicin did not change electrical potential or reactivity of rabbit caecum incubated with both amiloride and bumetanide. The administration of capsaicin on frog skin incubated with bumetanide casued inhibition of the reaction to mechanical stimulation, whereas during incubation with amiloride no changes were recorded in PD and dPD of the skin. The present study demonstrated that capsaicin and DMSO could modify processes of ion transport dependent on mechanical stimulation.


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    Tytuł oryginału: The prevalence of piroplasms in a population of Ixodes ricinus (Acari: Ixodidae) from North-Western Poland.
    Autorzy: Kuźna-Grygiel Wanda, Bukowska Katarzyna, Cichocka Agnieszka, Kosik-Bogacka Danuta, Skotarczak Bogumiła
    Źródło: Ann. Agric. Environ. Med. 2002: 9 (2) s.175-178, il., tab., bibliogr. 24 poz.
    Sygnatura GBL: 313,158

    Hasła klasyfikacyjne GBL:
  • mikrobiologia

    Typ dokumentu:
  • praca doświadczalna
  • tytuł obcojęzyczny

    Streszczenie angielskie: Developmental forms of Babesia spp. were studied in isolated salivary glands of Ixodes ricinus, subjected to the Feulgen reaction. The same ticks were also host to Babesia microti, which was determined by PCR amplification with primers specific to the fragemnt of a gene encoding the nuclear small subunit ribosomal RNA (SS-rDNA). Presence of Babesia spp. was recorded in the salivary glands of 59.9 p.c. of ticks collected, both in nymphs and adults. PCR reactions specific to Babesia microti were positive in 1.9 p.c. of nymphs.

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